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The 1st term (2007) Researchers & Research Theme
   
Singo Iwami
Associate Professor, Faculty of Sciences
Kyushu University

Theoretical challenge to the AIDS vaccine development |SHIV experiment and mathematical model|

HIV infection is a chronic infection characterized by an extremely long disease progression. Therefore, in order to prevent the disease spread, we should develop an AIDS vaccine which is effective for a long time. Even now, although it has passed 26 years from the discovery of HIV, we have not developed an effective AIDS vaccine. In this research, by using both mathematical models and animal experiments, I try to understand and inspect immune responses against the infection in rhesus macaques experimentally and theoretically. And, from a view point of theoretical immunology, I search and propose a new idea to develop the vaccine.
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