Hamada Team　　Result

(25) 2011Takaoka, K., Yamamoto, M. and Hamada, H. (2011). Origin and role of distal visceral endoderm, a group of cells that determines anterior-posterior polarity of the mouse embryo. Nat. Cell Biol.2011 May 29 13(7) 743-52.

(24) 2011Kawasumi, A., Nakamura, T., Iwai, N., Yashiro, K., Saijoh, Y., Belo, J.A., Shiratori, H. and Hamada, H. (2011). Left-right asymmetry in the level of active Nodal protein produced in the node is translated into the asymmetry in the lateral plate of mouse embryo. Dev Biol. in press. (DOI:10.1016/j/ydbio.2011.03.009)

(23)2010 Floro, K.L., Artap, S.T., Preis, J.I., Sparrow, D.B., Fatkin, D., Chapman, G., Furtado, M.B., Harvey, R.P., Hamada, H. and Dunwoodie, S.L. (2010). Loss of Cited2 causes congenital heart defects by perturbing left-right patterning of the body axis. Human Mol. Genetics.20(6) 1097-1110

(22)2010 Furtado, M.B., Biben, C., Shiratori, H., Hamada, H. and Harvey, R. P. (2010). Characterization of Pitx2c expression in the mouse heart using a reporter transgene. Dev. Dyn. 195-203.

(21)2010 . Bleyl, S.B., Saijoh. Y., Bax, N., Gittenberger-de Groot, A.C., Wisse, L.J., Chapman, S.C., Hunter, J., Shiratori, H., Hamada, H., Shiota, K., Klewer, S.E., Leppert, M.F., and Schoenwolf, G.C. (2010). Dysregulation of the PDGFRA gene causes inflow tract anomalies including TAPVR: Integrating evidence from human genetics and model organisms. Human Mol. Genetics. 19(7):1286-1301(epub. Jan. 13)

(20)2010 Hashimoto, M., Shinohara, K., Wang, J., Ikeuchi, S., Meno, C., Yoshiba, S., Takada S., Hatta, K., Wynshaw-Boris, T., and Hamada, H. (2010). Planar polarization of the nseisikibann ode cells determines the rotation axis of the node cilia. Nat Cell Biol. 12:170-176

(19)2009 Nakazato K, Mochizuki A. Steepness of thermal gradient is essential to obtain a unified view of thermotaxis in C. elegans. J Theor Biol. 2009, 260(1):56-65.

(18)2009 Oki, S., Kitajima, K., Belo, J.A., Yokoyama, T., Hamada, H.* and Meno, C.* (2009). Reversal of left-right asymmetry by aberrant Nodal signaling in the node of mouse embryos in the mouse embryo. (*corresponding authors). Development, 136:3917-3925

(17)2009 Uehara, M., Yashiro, K., Takaoka, K., Yamamoto M., and Hamada, H. Removal of maternal retinoic acid by embryonic CYP26 for correct Nodal regulation during early embryonic patterning. Genes & Dev. 23:1689-1698.

(16) Mar.23-25 2009 Invitation Lecture: "The origin of body axes in the mouse embryo" kobe,CDB Symposium on Sharpe and Polarity.

(15) Jan.12-13 2009 Invitation Lecture: [The origin of body axes in the mouse embryo]. 7th TLL Symposium, Singapore.

(14) Nov.17-21 2008 Invitation Lecture:[Long-range transfer of Nodal signal within the mouse embryo].2008.11.17-11.21. Okinawa Institute of Science and Technology. Gradient and Signaling : from chemotaxis to development.

(13) Oct.29-Nov.2 2008 Invitation Lecture:[The origin of body axes in the mouse embryo]. Cold Spring Harbor, USA. Mouse Genetics & Genomics: Development and Diseases.

(12) Sep.13-17 2008Invitation Lecture: [The origin of body axes in the mouse embryo]. (plenary) Giens, France. Frontiers in Developmental Biology.

(11) 2008 Yamamoto M., Beppu, X., Takaoka, K., Meno, C., Li, E., Miyazono, K., and Hamada, H. (2009). Antagonism between Smad1 and Smad2 signaling regulates formation of the distal visceral endoderm in the mouse embryo. J. Cell Biol. Jan 26;184(2):323-34.2009 Epub 2009 Jan 19.

(10) 2008 Shiba, D., Yamaoka, Y., Hagiwara, H., Takamatsu, T., Hamada, H., and Yokoyama, T. (2008). Localization of the Inv protein in a distinctive intra-ciliary compartment requires the C-terminal ninein-homolog containing region. J. Cell. Sci. 122:44-54.

(9) Oct.1-3 2007 Invitation Lecture:"The origin of body axes in the mouse embryo"at the Workshop on regulation of pluripotency during life cycle. Baeza, Spain

(8) Jul.14-19 2007 Invitation Lecture:"Regulation of Nodal signaling range in the mouse embryo" at the FASEB summer research conference on “TGF? superfamily: signaling and development”, Tucson, Arizona, USA.

(7) 2007 Sugimura K, Shimono K, Uemura T, Mochizuki A. (2007). Self-organizing mechanism for development of space-filling neuronal dendrites. PLoS Comput Biol. 3(11):e212.

(6) 2007 Tanaka, C., Sakuma, R., Nakamura, T., Hamada, H.*, and Saijoh, Y. (2007). Long-range action of Nodal requires interaction with GDF1. (*corresponding author). Genes & Dev 21:3272-3282.

(5) 2007 Oki, S., Hashimoto, R., Otani, H., Shen, M., Saijoh, Y., and Hamada, H. (2007). Sulfated glycosaminoglycan is necessary for Nodal signal transmission from the node to the left lateral plate in the mouse left-right patterning. Development,134:3893-3904.

(4) 2007 Prall, OW, Menon, MK., Solloway, MJ., Zaffran, S., Bajolle, F., Watanabe, Y., Biben, C., McBride, JJ., Robertson, BR., Chaulet, H., Stennard, FA.,Wise, N., Shiratori,H., Hamada,H., Black,BL., Saga,Y., Robertson, EJ., Buckingham, ME., Harvey , RP.(2007). Nkx2-5-dependent negative feedback loop affecting Bmp2/Smad1 balances cardiac progenitor cell specification and proliferation and is a molecular target in congenital heart disease. Cell 128:947-959.

(3) Nov.8 2007 Kenta Yashiro,Hidetaka Shiratori and Hiroshi Hamada "Haemodynamics determined by the genetic programme goven asymmetric development of the aortic arch" Nature (2007).

(2) 2007 Takeuchi, J.K., Lickert, H., Bisgrove, B., Yamamoto, M., Chawengsaksophak, K., Hamada, H., Yost, J., Rossant, J., and Bruneau (2007). Integration of Notch signaling at the node by Baf60c initiates the left-right asymmetry cascade. Proc. Natl. Acad. Sci. USA. 104:846-851.

(1) 2006 Nakamura, T., Mine , N., Nakaguchi, E., Mochizuki, A., Yamamoto, M., Yashiro, K., Meno, C., Hamada, H. (2006). Generation of robust left-right asymmetry in the mouse embryo requires a self enhancement lateral inhibition system. Dev Cell. 11:495-504.