Research Director

Junken Aoki

Tohoku University
Professor
website

Outline

It has been revealed that lysophospholipids have pivotal role in both physiological and pathological conditions as so-called second-generation lipid mediators. They include lysophosphatidic acid (LPA), sphingosine-1-phosphate (S1P) and lysophosphatidylserine (LysoPS). In this study we try to identify disease-related lysophospholipids by determining the lysophospholipid level in various clinical samples using a mass spectrometry with high sensitivity. We also apply these disease-related lysophospholipids to the identification of biomarkers and the drug discovery, thus contributing to medicine and health care.