[Yoshihiro Ogawa] Regulatory Mechanism Underlying Tissue Fibrosis Induced through Local Cell-Cell Interaction and Systemic Organ Network and Its Medical Applications


Research Director

Yoshihiro Ogawa

Yoshihiro Ogawa, M.D., Ph.D.

Tokyo Medical and Dental University
Professor


Outline

Tissue fibrosis, a common feature of chronic inflammatory diseases, may often result in the malfunction of a variety of organs and eventually organismal death. This study is designed to elucidate the molecular mechanism underlying tissue fibrosis, which occurs through the dysregulation of homeostatic mechanisms; local cell-cell interaction and systemic organ network. Accordingly, we wish to identify novel biomarkers and drug targets against non-alcoholic steatohepatitis (NASH), which may lay the groundwork for its preemptive medicine and innovative anti-fibrotic strategies.


Yoshihiro Ogawa_project_figure

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