Manufacturing of Polymeric Nanoparticle Vaccines with Control Capability of Immune Responses

Research Project Outline

This project is aimed at the development of biodegradable polymer-based nanoparticles with control capability of immune responses, and the establishment of manufacturing technology and pharmaceutical process for practical applications of polymeric nanoparticle vaccines. We design and prepare a safe and universal nanoparticle-based vaccine using nanoparticles capable of controlling intracellular kinetic of antigens and having adjuvant activity. This strategy will provide a novel immune therapy for infectious diseases, cancers, and autoimmune diseases.

Related Links

• Laboratory Website: http://www.chem.eng.osaka-u.ac.jp/~akashi-lab/Home_e/index.html