Measurement of Biological-single-molecule Dynamics by Carbon-nanotube Devices

Research Project Outline

Biological reactions proceed with various intermolecular interactions and energy transfer among molecules. This study is intended to develop devices to detect molecular mass shift (10-21 g), two-dimensional force (10-12 N), and heat flux (10- 19 J) at the single-molecule level using the superior electromechanical properties of carbon nanotubes. This study establishes techniques to analyze the molecular kinetics of various enzymatic reactions at a time resolution of several milliseconds. These devices and techniques will be applied to develop highly sensitive sensors, nanomachines, and nanomedical devices.

Related Links

• Laboratory Website: http://www-ne.mech.eng.osaka-u.ac.jp/Nakayamalab/english/home_e.html