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Researchers for the future

  • January, 2013

    Photo:Katsuhiko Hayashi

    Katsuhiko Hayashi

    To generate reproductive cells from mouse ES/iPS cells

    A research group including Dr. Katsuhiko Hayashi at Kyoto University succeeded in differentiating male mouse ES cells and iPS cells into primordial reproductive cells in vitro and induced sperms from the cells, to give healthy pups by in vitro fertilization in 2011. In 2012, they differentiated female mouse ES cells and iPS cells into primordial reproductive cells in vitro, grew them in culture with fetal mouse somatic cells that were to be ovaries, and transplant the cells into ovaries of other mice, to obtain unmatured ova. Then they grew the unmatured ova in vitro into mature ova, and give pups with these ova by in vitro fertilization. These studies on differentiation of ES or iPS cells into reproductive cells can contribute to developing reproductive medicine for humans in the future and therefore attracts attention in various related fields.

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How the important people view?

  • May, 2011

    Photo:Masayo Takahashi

    Masayo Takahashi

    To lead iPS cell research for clinical applications (1) -All 2 episodes-

    In ophthalmology, regenerative medicine using pluripotent stem cells will be introduced into clinical settings out of laboratory soon. Dr. Takahashi Masayo, expected as one of those who will be leading this field of research, first saw stem cells in the US about 15 years ago, and immediately became convinced that such cells can be used for retinal regeneration. She was the first researcher in the world who succeeded in generating retinal cells and retinal pigment epithelial cells (RPECs), first from ES cells, and then from iPS cells. She is now busy preparing to put retinal regenerative medicine into practice. She is confident that many patients will be saved by regenerative medicine, and continues her research.

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  • MEXT
  • Japan Science and Technology Agency
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