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| Research
Directors |
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Prof. Kouki
Horikoshi
Dept. of
Engineering, Applied Chemistry, Toyo University |
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formerly,Keiji Yano
Dept. of Agriculture, The University
of Tokyo |
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Prof. James
Tiedje
Center for
Microbes Morphology, Michigan State University |
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Counterpart Organization: Michigan State University
(U.S.A.)
Supporting National Agency: National Science Foundation
(NSF) |
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| Man-made chemical compounds did not exist
in previous environment and it is presumed that microbe that
degrade the compounds, are rapidly evolving the degradation
ability during the past several decades. Therefore, it is
expected that a precious knowledge on the evolutionary mechanism
of bacteria can be obtained when the microorganisms that degrade
those chemical compounds are examined. From this viewpoint,
this Microbial Evolution Project was conducted. |
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| As a result, various new PCB-degrading bacteria
were identified and those enzymes and genes were examined.
Consequently, the concept of the multi-gene family of degradation
genes was clarified for the first time, enabling successful
analysis of degradation mechanism of the powerful PCB-degrading
bacteria and elucidation of the three-dimensional structure
of the degrading enzyme. |
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