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Past Projects
RNA
ATP
Ultrashort Pulse Laser
Spatio-Temporal
Membrane Mechanisms
Quantum Spin Information
Organ Regeneration
Computational Brain
Nanoscale Quantum Conductor Array
Dynamic Nanomachine
Entropy Control
Calcium Oscillation
Photon Craft
Cell Mechanosensing
Bio-Recycle
Quantum Entanglement
Development of HIV/AIDS vaccine for HIV-1 Subtype-E
Single Molecule Processes
Nanotubulites
Chemotransfiguration
Cold Trapped Ion
Mind Articulation
NeuroGenes
Ceramics Superplasticity
Quantum Transition
Subfemtomole Biorecognition
Supermolecules
Microbial Evolution
Atom Arrangement-Design and Control for New Materials
1991.3~1996.3 Microbial Evolution Project
Japan-U.S.A.
Research Directors
Prof. Kouki Horikoshi Prof. Kouki Horikoshi
Dept. of Engineering, Applied Chemistry, Toyo University
     
    formerly,Keiji Yano
Dept. of Agriculture, The University of Tokyo
Prof. James Tiedje   Prof. James Tiedje
Center for Microbes Morphology, Michigan State University

Counterpart Organization: Michigan State University (U.S.A.)
Supporting National Agency: National Science Foundation (NSF)

Man-made chemical compounds did not exist in previous environment and it is presumed that microbe that degrade the compounds, are rapidly evolving the degradation ability during the past several decades. Therefore, it is expected that a precious knowledge on the evolutionary mechanism of bacteria can be obtained when the microorganisms that degrade those chemical compounds are examined. From this viewpoint, this Microbial Evolution Project was conducted.
As a result, various new PCB-degrading bacteria were identified and those enzymes and genes were examined. Consequently, the concept of the multi-gene family of degradation genes was clarified for the first time, enabling successful analysis of degradation mechanism of the powerful PCB-degrading bacteria and elucidation of the three-dimensional structure of the degrading enzyme.
Japan Science and Technology Agency
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