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Infectious Diseases Control

Determine the Outbreak Mechanisms and Development of a Surveillance Model for Multi-Drug Resistant Bacteria Elucidating the Mechanisms behind Super Resistant Bacteria, and Stemming Their Spread

Principal Investigator (Affiliation)
  • SDGs3
Guest Prof.
YAMAMOTO Yoshimasa
(Osaka University Global Collaboration Center)
Research Institutions in Japan Osaka University Global Collaboration Center / Osaka Prefectural Institute of Public Health / Osaka Prefecture University / University of the Ryukyus
Research Institutions in Vietnam National Institute of Nutrition (NIN), etc.
Adoption fiscal year FY 2011
Research Period 5 Years
ODA Recipient Country Socialist Republic of Vietnam
General Description of the Research Project

Tackling the worldwide threat of super resistant bacteria
With the emergence in recent years of super resistant bacteria that display resistance to therapeutic drugs, the number of untreatable infectious diseases is rising rapidly worldwide. The emergence of such bacteria is thought to have been driven by excessive use of antibiotics in livestock and fishery industries as well as healthcare. The spread of super resistant bacteria beyond national borders necessitates a global response. This project is focused on Vietnam, where the number of people infected with drug-resistant bacteria is growing dramatically. We are analyzing infection mechanisms, and aim to identify and investigate improper use of antibiotics and other factors causing the spread of super resistant bacteria.

Multifaceted analysis of the factors driving emergence of super resistant bacteria
We are analyzing the factors and mechanisms driving the emergence of super resistant bacteria from anthropological perspectives that consider socioeconomic factors in Vietnam as well as from microbiological and pharmacological perspectives. Based on our findings, we plan to help curb the worldwide spread of super resistant bacteria by building a resistant bacteria monitoring system.

Photo gallery
Antibiotic sensitivity experiment: once a bacterium develops multiple drug resistance, almost no antibiotics are effective against it.

Antibiotic sensitivity experiment: once a bacterium develops multiple drug resistance, almost no antibiotics are effective against it.

Domestic ducks raised in Vietnam

Domestic ducks raised in Vietnam

One of the proposed sampling sites

One of the proposed sampling sites

Research Project Web site http://www.phs.osaka-u.ac.jp/satreps/english/index.html
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