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Infectious Diseases Control

Principal Investigator (Affiliation)
  • SDGs3
Prof.
YAMAOKA Shoji
(Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University)
Research Institutions in Japan Tokyo Medical and Dental University / Nagasaki International University
Research Institutions in Ghana Noguchi Memorial Institute for Medical Research (NMIMR) / Center for Scientific Research into Plant Medicine (CSRPM)
Adoption fiscal year FY 2009
Research Period 5 Years
ODA Recipient Country Republic of Ghana
General Description of the Research Project

Finding substances in Ghanaian herbs that are effective against infectious diseases
Understanding and availability of advanced healthcare are still limited in Ghana, and lack of modern therapies is driving the spread of HIV, malaria, and other diseases. To address this problem, we are seeking to isolate substances effective in suppressing the replication of viruses and multiplication of parasites from herbs native to Ghana that have been traditionally used as therapies for infectious diseases. We aim to develop sustainable therapies tailored to Ghana's circumstances by elucidating the mechanisms by which beneficial substances exert their effects.

Effective substances successfully extracted from herbs
We have found several herb extracts that are useful in HIV infection control, and have also pinned down active components capable of suppressing the proliferation of Trypanosoma parasites. The next step is to aim for drug development, including evaluating these components in animal studies and elucidating their working mechanisms. As we do this, we will proceed with technology transfer, in order to ensure that research and development capacities become established and can grow.

Photo gallery
The protozoon parasite Trypanosoma brucei

The protozoon parasite Trypanosoma brucei

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Young Ghanaian researchers receiving training from Japanese specialists at the Noguchi Memorial Institute for Medical Research's Parasitology Department

Young Ghanaian researchers receiving training from Japanese specialists at the Noguchi Memorial Institute for Medical Research's Parasitology Department

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