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ERATO
Exploratory Research for Advanced Technology 
戦略的創造研究推進事業(総括実施型研究)
創造科学犠実推進事業
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HOME > Research Projects > Ongoing Projects > YOMO Dynamical Micro-scale Reaction Environment
YOMO Dynamical Micro-scale Reaction Environment
Research Director: Tetsuya Yomo
Graduate School of Information Science and Technology Osaka University.
Research Term 2009-2014
 
Outline of Research

  Life is frequently defined as an “evolvable and self-sustainable chemical reaction system.” This definition, however, is not widely accepted and represents not all the characteristics of cell, the natural dynamic micro-reactor. The aim of this project is to construct an artificial micro-reactor demonstrating the dynamical properties of natural cells from identified materials. We focus on three dynamic properties: 1) stochasticity, high efficiency, and robustness of internal reactions; 2) recursivity by growth and division; and 3) evolvability by mutation and selection. We compare the constructed artificial micro-reactor with a bacterium, Escherichia coli, to identify the differences and similarities between the artificial and natural dynamic micro-reactors. The construction and comparison will provide a new concept of the “cell” as the minimum unit of life, leading to the design principles for an artificial cell. This project requires interdisciplinary collaboration among various fields such as cell biology, biochemistry, physicochemistry, theoretical biology, and micro- or nanoengineering. This collaboration will cultivate young researchers who will open a new field of science.

 
Members
Research Director
Tetsuya Yomo
Research Groups
Compartmentalized reaction dynamics
Group Leader:
 Tomoaki Matsuura
Researcher:
 Satoshi Fujii
Dynamic reaction compartments
Group Leader:
 Hiroaki Suzuki
Researcher:
 Tetsuo Ichii
Evolutonary Programming
Group Leader:
 Norikazu Ichihashi
Researcher:
 Kimihito Usui
Organization of in liposome reaction group
Group Leader:
 Takeshi Sunami
Researcher:
 Takehiro Nishikawa
Characteristics of Micro-scale Reaction environment Group Leader:
 Tetsuya Yomo
Researcher:
 Taiji Okano



Project Office
Graduate School of Information Science and Technology Osaka University.
1-5 Yamadaoka,Suita,Osaka 565-0871. Japan

Research Manager
Yasuaki Kazuta
Administrative Manager
Takeshi Nomoto
Assistant
Mika Okazaki
Contact
Phone: +81 (0) 761 51 5800
FAX: +81 (0) 761 51 5889


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Exploratory Research for Advanced Technology 
戦略的創造研究推進事業(総括実施型研究)
創造科学技術推進事業 ERATO