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MIYAWAKI Life Function Dynamics
Research Director: Dr. Atsushi Miyawaki
Research Term 2006-2011
Outline of Research

  Well-concerted morphogenesis and physiological activity as the whole body are realized by spatiotemporally proper functions and communications of individual cells. In this project, we aim to elucidate the mechanism of dynamic cell functions such as proliferation, migration and differentiation by inspecting them particularly in the living body. To achieve the aim, we innovate and apply the technology for in vivo optical imaging. Firstly, we create the novel probe molecules to detect the cellular activity as changes in intensity and color of fluorescence or luminescence. Secondly, we develop and improve the imaging systems that visualize the signals emitted from the probes with three-dimensionally high resolution. Ultimately, we will clarify how the cellular activity is controlled in the body by analyzing the events with mathematical models.

Research Director
Dr. Atsushi Miyawaki
Research Groups
In VivoLive Imaging Researcher:
 Asako Sakaue
 Kazuki Sasaki
 Tetsuya Kitaguchi
 Nagatoki Kinoshita
 Hiroyuki Katayama
Research Assistant:
 Yukiko Kumagai
 Yoshiko Wada
 Hiromi Ohtsuka
 Miyuki Ito
Optical System Development Group Leader:
 Hiroyuki Kawano
 Tetsushi Hoshida

Project Office
Laser Science Laboratory, RIKEN
2-1 Hirosawa, Wako, Saitama, 351-0198, JAPAN
Research Manager:
 Masahiko Hirano
Administrative Manager:
 Masatoshi Takahashi Assistant:
 Naoko Nomoto
Phone: +81 (0) 48 451 3011
FAX: +81 (0) 48 463 6900

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