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ERATO
Exploratory Research for Advanced Technology 
戦略的創造研究推進事業(総括実施型研究)
創造科学犠実推進事業
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HOME > Research Projects > Ongoing Projects > HASEBE Reprogramming Evolution
HASEBE Reprogramming Evolution
Research Director: Dr. Mitsuyasu Hasebe
(Professor, National Institute for Basic Biology, National Institutes of Natural Sciences) Research Term 2005-2011
 
Outline of Research

  Some plants have a very interesting property: if a piece of leaf is placed in the soil, an entire plant will grow from it, as if from a seed. The leaf cells are “reprogrammed” such that the pattern of gene expression in the differentiated cells is reset to that of a cell with the ability to begin the regular developmental process, such as a stem cell.

  This project seeks to understand the molecular mechanisms underlying the plastic nature of plant cells. We used the moss Physcomitrella patens as a model because of its high reprogramming rate, the ease of observing the reprogramming process, and the feasibility of making genetic modifications using gene targeting techniques. The mechanisms we hope to reveal can be applied to other organisms without this ability.

 
Members
Research Director
Dr. Mitsuyasu Hasebe
Research Groups
Omics Group Leader:
 Mitsuyasu Hasebe
Reverse Genetics Group Leader:
 Tomoaki Nishiyama




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Exploratory Research for Advanced Technology 
戦略的創造研究推進事業(総括実施型研究)
創造科学技術推進事業 ERATO