TAKEDA Yoichi
Biofunctional Glycochemistry Group Leader
- Year of Birth: 1975 (born in Onbetsu, Hokkaido, Japan)
- Degree: Ph.D. (Engineering), Tokyo University of Science
Education
- 1999
- Graduated from Tokyo University of Science
- 2005
- Completed Doctoral Course at Tokyo University of Science Graduate School of Industrial Science and Technology
Experience
- 2005-2006
- Postdoctoral Fellow in the Group of Prof. K. Sakurai, JST- The University
of Kitakyushu
- 2006-2007
- Postdoctoral Fellow in the Group of Prof. K. Sakurai, NEDO- The University of Kitakyushu
- 2007-2009
- Postdoctoral Fellow in the Group of Dr. Y. Ito, RIKEN ASI
- 2009-
- Researcher of ERATO Ito Glycotrilogy Project, JST
| Membership of Academic Society |
- The Chemical Society of Japan
- The Japanese Society of Carbohydrate Research
| Publications |
| Kohki Fujikawa, Akihiko Koizumi, Masakazu Hachisu, Akira Seko, Yoichi Takeda and Yukishige Ito. Construction of a High-Mannose-Type Glycan Library
by a Renewed Top-Down Chemo-Enzymatic Approach. Chem. Eur. J. 21, 3224-3233, (2015). |
| Fang Zhang, Mominul M.Hoque, Jiandong Jiang, Kaoru Suzuki, Masaru Tsunoda, Yoichi Takeda, Yukishige Ito, Gota Kawai, Haruo Tanaka and Akio Takénaka. The Character.
ChemBioChem 15, 2766-2773 (2014). |
| Masafumi Sakono, Akira Seko, Yoichi Takeda, and Yukishige Ito. PDI family protein ERp29 forms 1:1 complex with lectin
chaperone calreticulin. Biochem. Biophys. Res. Commun. 452, 27-31 (2014). |
| Shogo Iwamoto, Yuta Kasahara, Ken-ichi Kamei, Akira Seko, Yoichi Takeda, Yukishige Ito, and Ichiro Matsuo. Measurement of endo-α-mannosidase activity
using a fluorescently labeled oligosaccharide derivatives. Biosci. Biotech. Biochem. 78, 927-936 (2014). |
| Masafumi Sakono, Akira Seko, Yoichi Takeda, Jun-ichi Aikawa, Masakazu Hachisu, Akihiko Koizumi, Kohki Fujikawa, and Yukishige Ito. Glycan specificity of a testis-specific lectin chaperone calmegin and effects of hydrophobic interactions.Biochimica et Biophysica Acta (BBA) - General Subjects 1840, 2904-2913, (2014).
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| Jun-ichi Aikawa, Yoichi Takeda, Ichiro Matsuo, and Yukishige Ito. Trimming of glucosylated N-glycans by human ER α1,2-mannosidase I.J. Biochem. 155, 375-384, (2014). |
| Yoichi Takeda, Akira Seko, Masakazu Hachisu, Shusaku Daikoku, Masayuki Izumi, Akihiko
Koizumi, Kohki Fujikawa, Yasuhiro Kajihara, and Yukishige Ito. Both Isoforms
of Human UDP-glucose:glycoprotein Glucosyltransferase are Enzymatically
Active.Glycobiology, 24, 344-350, (2014). |
| A. Koizumi, I. Matsuo, M. Takatani, A. Seko, M. Hachisu, Y. Takeda, Y. Ito. Top-Down Chemoenzymatic Approach to a High-Mannose-Type Glycan Library: Synthesis of a Common Precursor and Its Enzymatic Trimming.Angewandte Chemie.52, 7426-7431, (2013). |
| Takeda, Y., Seko, A., Sakono, M.,
Hachisu, M., Koizumi, A., Fujikawa, K., Ito, Y. Parallel quantification of
lectin-glycan interaction using ultrafiltration.Carbohydr. Res.375, 112-117, (2013). |
Masafumi Sakono, Akira Seko, Yoichi Takeda, Masakazu Hachisu, Yukishige Ito. Biophysical properties of UDP-glucose:glycoprotein
glucosyltransferase,
a folding sensor enzyme in the ER, delineated by synthetic probes. BBRC, 426, 504-510, (2012). |
| Ito, Y. & Takeda, Y. Analysis of
glycoprotein processing in the endoplasmic reticulum using synthesis
oligosaccharides. Proc. Jpn. Acad., Ser. 88, 31-40, (2012). |
| Takeda, Y., Totani, K., Matsuo, I.
& Ito, Y. Chemical approaches toward understanding glycan-mediated protein
quality control. Curr Opin Chem Biol 13, 582-591, (2009). |
| Takeda, Y., Shimada, N., Kaneko,
K., Shinkai, S. & Sakurai, K. Ternary complex consisting of DNA,
polycation, and a natural polysaccharide of schizophyllan to induce cellular
uptake by antigen presenting cells. Biomacromolecules
8, 1178-1186, (2007). |
| Takeda, Y. & Horito, S.
Synthesis of alpha-series ganglioside GM1alpha containing C20-sphingosine. Carbohydr. Res. 340, 211-220, (2005). |
| Review, Book chapter |
| Takeda, Y. & Matsuo, I. Isothermal Calorimetric Analysis of Lectin–Sugar Interaction.Lectins 1200, 207-214, (2014). |
| Ito Y, & Takeda Y. Deciphering the Roles of Glycan Processing in Glycoprotein Quality Control through Organic Synthesis. Biosci Biotechnol Biochem. 77, 2331-2338, (2013). |
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Japanese