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Japan Science and Technology Agency.

CREST
Creation of a novel technology towards diagnosis and treatment based un understanding of molecular pathogenesis of psychiatric and neurological disorders
Research Themes, Principle Investigators

Onodera Team

Researcher's name Onodera Hiroshi
assisatant director,National Nishitaga Hosipital
Research Themes Novel approach to reconstruct neuronal circuits after spinal cord injury and brain diseases

Content

Although innovations in neuronal stem cell science are amazing, neuronal cell transplantation techniques are still unsatisfactory. This is partly because of insufficient neurite outgrowth of grafted neurons in the host tissues. We develop a method to encourage neurite extension in damaged neuronal tissues by utilizing cell adhesion molecules-bound magnetic substances, which can be arranged in the putative neuronal circuites in the host tissues suffering from spinal cord injury or brain diseases.