Home > Topics & News
TOPICS
18th, September, 2014The article of Principal Researcher Dr. Nobuyuki Takakura (Professor, Kyoto University) was published on September 18, 2014 in "Nature" on line. The title of the article was "Statin treatment rescues FGFR3 skeletal dysplasia phenotypes."abstruct(Pubmed)
16th, June, 2014The article of Principal Researcher Dr. Yutaka Hanazono (Professor, Jichi Medical University) was published on June 16, 2014 in "PLOS ONE" on line. The title of the article was "MHC-Matched Induced Pluripotent Stem Cells Can Attenuate Cellular and Humoral Immune Responses but Are Still Susceptible to Innate Immunity in Pigs." abstruct(Pubmed)
11th, June, 2014The article of Principal Researcher Dr. Masaki Ieda Project Assistant Professor, Keio University) was published on June 11, 2014 in "EMBO J." on line. The title of the article was "MiR‐133 promotes cardiac reprogramming by directly repressing Snai1 and silencing fibroblast signatures." abstruct(Pubmed)
26th, February, 2014The article of Principal Researcher Dr. Hideyuki Saya (Professor, Keio University) was published on February 26, 2014 in "Nature Communications". The title of the article was "Regulation of MKL1 via actin cytoskeleton dynamics drives adipocyte differentiation." abstruct(Pubmed)
7th, February, 2014The article of Principal Researcher Dr. Shunsuke Ishii (Distinguished Senior Scientist, RIKEN) was published on February 7, 2014 in "Cell Stem Cell". The title of the article was "Histone Variants Enriched in Oocytes Enhance Reprogramming to Induced Pluripotent Stem Cells." abstruct(Pubmed)
19th, December, 2013The article was selected one of The 2013 Best Manuscript Awards from articles published between July 2012 and June 2013 based on novelty, impact, data quality, & number of online downloads by Circulation Research readers.Circulation Research
29th, August, 2012
The article of Principal Researcher Dr. Masaki Ieda (Project Assistant Professor, Keio University) was published on August 29, 2012 in "Circulation Research" on line. The title of the article was "Induction of Cardiomyocyte-like Cells in Infarct Hearts by Gene Transfer of Gata4, Mef2c, and Tbx5". abstruct(Pubmed)
13th, December, 2013The article of Co-Researcher Dr.Ryuichi Nishinakamura (Professor, Kumamoto University) was published on December 13, 2013 in "Cell Stem Cell". The title of the article was "Redefining the in vivo origin of metanephric nephron progenitors enables generation of complex kidney structures from pluripotent stem cells." abstruct(Pubmed)
17th, October, 2013The article of Principal Researcher Dr. Noriyuki Tsumaki (professor, Kyoto University) was published on October 17, 2013 in "PLOS ONE". The title of the article was "Direct induction of chondrogenic cells from human dermal fibroblast culture by defined factors." abstruct(Pubmed)
10th, October, 2013The article of Dr. Masahito Watanabe (a member of Co-Researcher Nagashima's group, Meiji University International Institute for Bio-Resource Research) was published on October 10, 2013 in "PLOS ONE". The title of the article was "Generation of Interleukin-2 Receptor Gamma Gene Knockout Pigs from Somatic Cells Genetically Modified by Zinc Finger Nuclease-Encoding mRNA." abstruct(Pubmed)
19th, September, 2013The article of Co-Researcher Dr. Tetsuya Suhara (Director, National Institute of Radiological Sciences) was published on September 19, 2013 in "Neuron". The title of the article was "Imaging of Tau Pathology in a Tauopathy Mouse Model and in Alzheimer Patients Compared to Normal Controls." abstruct(Pubmed)
30th, July, 2013The article of Principal Researcher Dr. Yoshihiro Yoneda (Director, National Institute of Biomedical Innovation) was published on July 30, 2013 in "Developmental Cell". The title of the article was "Importin Alpha Subtypes Determine Differential Transcription Factor Localization in Embryonic Stem Cells Maintenance." abstruct(Pubmed)
16th, July, 2013The article of Principal Researcher Dr. Masaki Ieda (Project Assistant Professor, Keio University) was published on July 16, 2013 in "PNAS". The title of the article was "Induction of Human Cardiomyocyte-like Cells from Fibroblasts by Defined Factors." abstruct(Pubmed)
3th, July, 2013The article of Principal Researcher Dr. Satoru Senju (Associate Professor, Kumamoto University) was published on June 3, 2013 in "PLOS ONE". The title of the article was "Therapeutic effect of human iPS-cell?derived myeloid cells expressing IFN-? against peritoneally disseminated cancer in xenograft models." abstruct(Pubmed)
7th, June, 2013The article of Principal Researcher Dr. Takashi Shinohara (Professor, Kyoto University) was published on June 7, 2013 in "Cell Stem Cell". The title of the article was "ROS Are Required for Mouse Spermatogonial Stem Cell Self-Renewal." abstruct(Pubmed)
22th, February, 2013The article of Principal Researcher Dr. Haruhisa Inoue (Associate Professor, Kyoto University) was published on February 22, 2013 in "Cell Stem Cell" on line. The title of the article was "Modeling Alzheimer's disease using iPSCs reveals stress phenotypes associated with intracellular A-beta and differential drug responsiveness." abstract(Pubmed)
21th, January, 2013The article of Principal Researcher Dr. Yutaka Hanazono (Prof, Jichi Medical University) was published on January 21, 2013 in "Stem Cells and Development". The title of the article was "Generation of Naive-Like Porcine-Induced Pluripotent Stem Cells Capable of Contributing to Embryonic and Fetal Development" abstract(Pubmed)
4th, January, 2013The article of Principal Researcher Dr. Haruhiko Koseki (Group Director, RIKEN) was published on January 4, 2013 in "Cell Stem Cell" on line. The title of the article was "Regeneration of human tumor antigen-specific T cells from iPS cells derived from mature CD8+ T cells" abstract(Pubmed)
2th, August, 2012The article of Principal Researcher Dr. Haruhisa Inoue (Associate Professor, Kyoto University) was published on August 2, 2012 in "Science Translational Medicine" on line. The title of the article was "Drug Screening for ALS Using Patient-Specific Induced Pluripotent Stem Cells". abstract(Pubmed)
7th, June, 2012The article of Principal Researcher Dr. Hideyuki Saya (professor, Keio University) was published on June 6, 2012 in "Nature Communication" on line. The title of the article was "Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell". abstract(Pubmed)
20th, January, 2012Principal Researcher Dr. Masaki Ieda (Project Assistant Professor, Keio University) was awarded the Eighth JSPS Prize on January 20, 2012 "Mechanisms of Heart Development and Regeneration". -Awardees-(JSPS) Research Theme
4th, November, 2011The article of Principal Researcher Dr. Noriyuki Tsumaki (professor, Kyoto University) was published on November 4, 2011 in "Cell Stem Cell" on line. The title of the article was "Rac mediates mouse spermatogonial stem cell homing to germline niches by regulating transmigration through the blood-testis barrier". abstract(Pubmed)
6th, January, 2012The article was selected one of Reaseach Highlights of 2011. Cell
5th, August, 2011
The article of Principal Researcher Dr. Mitinori Saitou (professor, Kyoto University) was published on August 5, 2011 in "Cell" on line. The title of the article was "Reconstitution of the Mouse Germ-Cell Specification Pathway in Culture by Pluripotent Stem Cells". abstract(Pubmed)
8th, July, 2011The article of Principal Researcher Dr. Akihiko Okuda (professor, Saitama Medical University) was published on July 8, 2011 in "Cell Stem Cell" on line. The title of the article was "Indefinite Self-Renewal of ESCs through Myc/Max Transcriptional Complex-Independent Mechanisms". abstract(Pubmed)
15th, March, 2011The article of Principal Researcher Dr. Hideyuki Saya (professor, Keio University) was published on March 15, 2011 in "Cancer Cell" on line. The title of the article was "CD44 Variant Regulates Redox Status in Cancer Cells by Stabilizing the xCT Subunit of System xc- and Thereby Promotes Tumor Growth". abstract(Pubmed)
11th, January, 2011The article of Principal Researcher Dr. Noriyuki Tsumaki (associate professor, Osaka University) was published on January 11, 2011 in "Journal of clinical investigation" on line. The title of the article was "Generation of hyaline cartilaginous tissue from mouse adult dermal fibroblast culture by defined factors". abstract(Pubmed)
25th, August, 2010The new themes of CREST in 2010 were decided.
2nd, June, 2010The article of Principal Researcher Dr. Haruhiko Koseki (group director, Riken) was published on June 2, 2010 in "Journal of clinical investigation" on line. The title of the article was "Murine induced pluripotent stem cells can be derived from and differentiate into natural killer T cells". abstract(Pubmed)
16th, March, 2010JST starts invitating of Research Proposal in 2010 for CREST and PRESTO. Details of invitation of the research proposal is opened. Web of Announcement
5th, March, 2010The article of Principal Researcher Dr. Atsushi Iwama (professor, Chiba University) was published on March 5, 2010 in "Cell Stem Cell". The title of the article was "Poised lineage specification in multipotential hematopoietic stem and progenitor cells by the polycomb protein Bmi1".abstract(Pubmed)
9th, December, 2009The article of Principal Researcher Dr. Mitsuo Oshimura (professor, Chiba University) was published on December 9, 2009 in "Molecular Therapy" on line. The title of the article was "Complete genetic correction of iPS cells from Duchenne muscular dystrophy". abstract(Pubmed)
17th, September, 2009The new themes of CREST in 2009 were decided.
2nd, July, 2009The article of Principal Researcher Dr. Hitoshi Niwa (team leader, Riken) was published on July 2, 2007 in "Nature" on line. The title of the article was "A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells". abstract(Pubmed)
2nd, July, 2009The article of Principal Researcher Dr. Takashi Shinohara (professor, Kyoto University) was published on July 2, 2007 in "Cell Stem Cell" on line. The title of the article was "Genetic Reconstruction of Mouse Spermatogonial Stem Cell Self-Renewal In Vitro by Ras-Cyclin D2 Activation". abstract(Pubmed)
Invitation of Research Proposal in 2009 for Basic Research ProgramsJST starts invitating of Research Proposal in 2009 for CREST and PRESTO. Details of invitation of the research proposal is opened. Web of Announcement
Symposium of ICORP Organ Regeneration Project 2009 at Tokyo (Collaborating with CREST iPS Cells Project)Joint symposiumu was held as below.
Place:Yasuda Auditorium, The University of Tokyo
Language:English
Program
[Opening]
Declaration: Makoto Asashima (University of Tokyo, ICORP)
Welcome Address: Koichi Kitazawa (President of JST)
[Keynote Lectures: Overview of the Collaborative Project (ICORP)]
Douglas A. Melton(Harvard University), Makoto Asashima
[Paper I: Exploring Regenerative Potential (ICORP)]
Amy Wagers (Harvard University) "Regenerative potential of skeletal muscle stem cells"
Hitoshi Okochi (International Medical Center of Japan) "Stem cells in the skin and regenerative medicine"
Kenji Osafune (Kyoto University, ICORP) "Towards the development of regenerative medicine for kidney diseases: Lessons from pancreas"
Akira Kurisaki (AIST, ICORP) "Regulation of pluripotency and self-renewal of mouse ES cells by a chromatin-related factor."
Konrad Hochedlinger (Harvard University) "Understanding nuclear reprogramming"
Hiromitsu Nakauchi (University of Tokyo)
[Paper II: Towards Clinical Applications (ICORP)]
Teruo Nishida (Yamaguchi University) "Restoration of the cornea: from the bench to clinic"
Mariko Yamaki (Matsumoto Dental University) "Collagen can suppress the potential of teratoma formation from ES cells"
Chad Cowan (Harvard University) "Modeling disease with pluripotent stem cells"
Kevin Eggan (Harvard University) "Using stem cells and reprogramming to understand neuro-degeneration"
Lee Rubin (Harvard University) "Making neurons from ES cells: A better way to study neurodegenerative disease?"
[Perspectives]
Douglas A. Melton, Makoto Asashima
[Paper III: New Frontier in Cellular Reprogramming (CREST)]
Introductory Speech: Toshio Suda (Keio University)
Mitsuo Oshimura (Tottori University) "Towards ideal iPS cells for gene therapy and regenerative medicine using a human artificial chromosome "
Haruhiko Koseki (RIKEN) "Isolation of molecular markers that represent pluripotency and tumorigenicity of human iPS cells"
Hideyuki Saya (Keio University) "Analysis of abnormal regulation of cell differentiation and drug development research by using induced cancer stem cells"
Takashi Shinohara (Kyoto University) "Analysis of reprogramming mechanism of Germline stem cells"
Hitoshi Niwa (RIKEN) "Analysis of the transcription factor network governing establishment of pluripotency in somatic cells"
------------------------------------------------------------------------------------------------------------------------
If you want to know the detail schedule, please check this pdf file.
