Reserach

Researchers

PRESTOCREST
  • FY 2010
  • FY 2011
  • FY 2012

  • Koji AOKI
  • Kenichi ASANO
  • Koji ATARASHI
  • Takaharu OKADA
  • Junko SASAKI
  • Katsuaki SATO
  • Takashi SHICHITA
  • Kazuhiro SUZUKI
  • Takashi TANAKA
  • Susumu NAKAE
  • Sachie HIRATSUKA
  • Kumiko MAKIDE
  • Tohru MINAMINO
  • Tadashi YOKOSUKA

Koji Atarashi – Control of intestinal Regulatory T cell by human commensal bacteria

Researcher

Koji Atarashi
Assistant Professor, Department of Microbiology and Immunology, School of Medicine, Keio University
http://www.ims.riken.jp/labo/48/index.html
Research Theme
Control of intestinal Regulatory T cell by human commensal bacteria

Inflammatory bowel disease (IBD) is a intractable disease, probably involving an over active immune response to intestinal tract. There is need to develop curative treatments for IBD. Recent studies have demonstrated that abnormal gut flora could be involved in the pathogenesis of IBD. These consider treatment by artificial manipulation of the intestinal bacteria . In this study, focusing on human gut bacteria, I will elucidate the mechanisms of induction and function of intestinal regulatory T cells and try to develop a novel therapeutic approach using human gut bacteria.

Research Results
The 5 Cardinal Signs of Inflammation