Researchers
Kazuyo Moro – Action mechanism of natural helper cells regulating the Th1/Th2 balance in IL-33-dependent chronic inflammatory diseases
Researcher
- Kazuyo Moro
- Team Leader, Center for Integrative Medical Sciences, Riken
Research Theme
Action mechanism of natural helper cells regulating the Th1/Th2 balance in IL-33-dependent chronic inflammatory diseases
IL-33 is released in the body during chronic inflammatory diseases. Natural helper (NH) cells, which we have recently identified, respond to IL-33 and produce large amounts of Th2 cytokines involved in various inflammatory processes. It is thus likely that NH cells play important roles in chronic inflammatory diseases. In this project, I will investigate the dynamics of NH cells in the body and the role of NH cells in chronic inflammation and develop a new strategy to control chronic inflammatory diseases by regulating the NH cell functions.