Reserach

Researchers

PRESTOCREST
  • FY 2010
  • FY 2011
  • FY 2012

  • Makoto ARITA
  • Tatsushi IGAKI
  • Naoko OHTANI
  • Masatsugu OH-HORA
  • Shinobu SAIJO
  • Tomohiro SAWA
  • Yuki SUGIURA
  • Kohsuke TAKEDA
  • Norihiko TAKEDA
  • Yasushi HIROTA
  • Kazuyo MORO
  • Masakatsu YAMASHITA
  • Hiroshi WATARAI

Kazuyo Moro – Action mechanism of natural helper cells regulating the Th1/Th2 balance in IL-33-dependent chronic inflammatory diseases

Researcher

Kazuyo Moro
Team Leader, Center for Integrative Medical Sciences, Riken
http://www.ims.riken.jp/labo/56/index.html
Research Theme
Action mechanism of natural helper cells regulating the Th1/Th2 balance in IL-33-dependent chronic inflammatory diseases

IL-33 is released in the body during chronic inflammatory diseases. Natural helper (NH) cells, which we have recently identified, respond to IL-33 and produce large amounts of Th2 cytokines involved in various inflammatory processes. It is thus likely that NH cells play important roles in chronic inflammatory diseases. In this project, I will investigate the dynamics of NH cells in the body and the role of NH cells in chronic inflammation and develop a new strategy to control chronic inflammatory diseases by regulating the NH cell functions.

Research Results
The 5 Cardinal Signs of Inflammation