Design of Molecular Acid Catalyst

Principal Investigator

Hisashi YAMAMOTO Professor, Chairman of,  Chubu University)

Co-Principal Investigator

Matsujiro AKAKURA (Associate professor, Aichi Educational University)

Outline of the Project

Enzyme is a giant molecule widely distributed in biological system, which is a crucial catalyst for making various biologically important molecules in living systems.  It was known that the true man-made mimics of these enzymes, “chemzymes” are exceedingly difficult to design and prepare.  The aim of the present project is to design and synthesis of truly useful chemzymes.  Specifically, new Lewis and Brønsted acid catalysts will be prepared and use them as synthetic catalysts for various chemical transformations, especially for asymmetric pathways to new carbon-carbon bond formations. 

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