Novel Activation and Synthetic Transformations of Stable Chemical Bonds by Means of Metal Catalysts

Principal Investigator

Tamejiro HIYAMA (Professor, Research and Development Initiative, Chuo University)

Co-Principal Investigator

Shin-ichi FUKUZAWA ( Professor, Faculty of Science and Engineering, Chuo University)
Ken SAKATA (Associate Professor, Hoshi University, School of Pharmacy and Pharmaceutical Sciences)

Outline of the Project

For the realization of sustainable human society in the future, it is essential to invent environmentally-benign organic reactions which allow us to suppress emission of CO2, energy consumption, and overuse of resources.
The present research project aims at invention of methods for the activation of stable chemical bonds such as carbon-hydrogen bonds in the presence of transition metal catalysts assisted by multiple bond coordination to achieve new carbon–carbon bond formation.  Our final goal is straightforward carbon-carbon bond formation by addition of organic substrate to alkenes without prefunctionalization and preferably in an asymmetric manner.  These novel reactions allow us to construct π-conjugated electron systems straightforwardly.  The present research will not only provide with new synthetic organic reactions but also contribute to green chemistry requested for the future.


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